According to camp sources, Boniface sustained a muscle injury in training but the extent is yet to known yet.
The 23-year-old missed the Super Eagles friendlies against Al Gharib and Guinea due to the injury.
Napoli hitman, Victor Osimhen and Real Sociedads Umar Sadiq are the only fit strikers in the squad at the moment.
The other striker in the team, Kelechi Iheanacho is also struggling to be fit for the AFCON.
Boniface made his debut for the Super Eagles against Sao Tome and Principe in September.
He has featured five times for the three-time African champions.
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