It is now nine league games without defeat for Leverkusen this season, winning eight and drawing one.
They usurp Bayern Munich at the top of the log and are on 25 points, just two points above the Bundesliga.
Boniface was on from the start before he was replaced in the 90th minute.
He had four shots and created four chances before going off.
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The former Union SG striker has scored seven goals in nine Bundesliga games.
Also, he is in fourth place in the leagues top scorers chart.
Leverkusen will be in action on Wednesday in the German Cup against lower division side Sandhausen.
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