Ndidi was not in Leicesters squad for Tuesdays away game against Sunderland as a result of a tightness in his muscle.
Speaking after the game against Sunderland, Maresca said Ndidi was rested and should be back for Saturdays game against QPR.
But in his presser on Friday he said that Ndidis injury is more serious than first thought, and he will miss out on this weekends game.
Its a bit more than tightness, he is out this weekend. It could be a few days, its a muscle problem, but it is not a big thing, Maresca was quoted on BBC Sport Leicester X.
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This would be a cause for worry for the Super Eagles coaching crew as they look forward to next months 2026 FIFA World Cup qualifiers.
The Eagles will host Lesotho on November 16 in their first Group C fixture in the qualifiers before traveling to Kigali, Rwanda, to face Zimbabwe on November 20 on match day two.
Star striker, Victor Osimhen is currently out after sustaining a hamstring injury during the Super Eagles friendly game with Saudi Arabia.
Ndidi has scored one goal, provided three assists in 12 games for Championship leaders Leicester.
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